Infection control and oral-systemic health have always been central to dental care, but emerging innovations continue to reshape how we view disease prevention. One such innovation gaining attention is antiviral chewing gum—a functional oral product that may soon help limit the transmission of viruses like influenza and herpes simplex through the mouth.
This breakthrough could significantly impact patient care, not only by enhancing infection control but also by broadening our approach to patient education and protection both inside and outside the operatory.
The Innovation: How Antiviral Chewing Gum Works
Developed by researchers at the University of Pennsylvania’s School of Dental Medicine, the gum uses a natural protein extracted from the lablab bean plant called FRIL (Flt3 receptor-interacting lectin). This protein works by binding to sugar molecules found on the surface of viral particles such as influenza A (H1N1, H3N2) and HSV-1 and HSV-2. Once bound, the virus is effectively trapped and neutralized.
In lab-based studies, chewing gum containing just 40 mg of the plant protein reduced viral load by over 95%. These results have sparked interest in the dental community, particularly given the oral cavity’s role in viral entry and shedding.
“The oral environment is the first line of contact for many pathogens,” explains Dr. Marielaina Perrone, DDS, a cosmetic and family dentist in Henderson, NV. “Using something as simple as chewing gum to interrupt viral transmission could be a game-changer—especially in high-contact professions like dentistry.”
Why This Matters in the Dental Office
While the product is still undergoing clinical trials, the theoretical benefits for dental settings are worth considering:
1. Additional Infection Control Layer
While dental offices already implement strict sterilization protocols, antiviral chewing gum could help reduce the oral viral load in patients—especially during flu season or among those with recurring cold sores.
2. Patient Education Opportunity
Dental professionals play a crucial role in educating patients about the oral-systemic connection. Introducing innovative tools like antiviral gum can reinforce this connection and empower patients to take control of their health.
“As dentists, we often catch signs of systemic disease early—whether it’s cold sores, oral ulcers, or general inflammation,” says Dr. Perrone. “The more preventive tools we have, the more empowered our patients become.”
3. Enhanced Safety for Clinicians and Staff
Any intervention that may reduce the presence of transmissible viruses in the oral cavity during treatment may enhance safety for dental teams, particularly during aerosol-generating procedures.
Viruses of Interest: Influenza and Herpes
- Influenza A: A highly contagious virus transmitted via saliva and respiratory droplets. Though seasonal, its spread in shared public spaces (like dental offices) poses yearly risks.
- Herpes Simplex Virus (HSV-1): A common virus that manifests as cold sores or oral lesions. These are often triggered by stress, illness, or trauma—including dental visits.
Both viruses are known to replicate or shed in the oral cavity, so intercepting them at that point could have meaningful public health implications.
What Dental Professionals Should Watch For
While antiviral gum is not yet commercially available, there are steps dental professionals can take now:
- Stay informed about ongoing clinical trials and developments.
- Review current infection control protocols and see where such a product could enhance existing safety layers.
- Educate patients on emerging oral-systemic innovations.
- Be prepared to integrate such tools into your patient care strategy if and when they receive FDA approval.
“We’ve learned through COVID-19 just how quickly science can evolve,” Dr. Perrone notes. “It’s our responsibility to remain adaptable and lead with science-backed strategies.”
Conclusion: Innovation Meets Prevention
Antiviral chewing gum represents an exciting intersection of dentistry, public health, and biotechnology. While it won’t replace standard infection control, it could serve as an accessible, noninvasive adjunct to help mitigate disease transmission, especially in oral healthcare environments.
For dental professionals, the takeaway is clear: staying engaged with innovations like antiviral gum strengthens clinical care and reinforces the profession’s vital role in holistic health and disease prevention.
About Dr. Marielaina Perrone, DDS
Dr. Marielaina Perrone is a trusted cosmetic and general dentist in Henderson, NV, with over 20 years of experience. Her expertise includes smile makeovers, dental implants, and preventive care for patients with complex medical needs. She is passionate about the intersection of dental and systemic health and routinely shares her insights on emerging research and innovations.