Graphene-Enhanced Polymers Boost Prosthodontic Performance

Posted: September 23, 2025
In recent years, the integration of graphene into dental biomaterials for prosthodontic applications has sparked significant interest. A systematic review and meta-analysis sought to evaluate the impact of graphene-incorporated nanofillers on the mechanical properties of polymers used in prosthodontics. The review aimed to determine whether the addition of graphene or its derivatives, even at low concentrations, could enhance material performance without compromising biocompatibility. Through a comprehensive search across PubMed, Web of Science, Cochrane Library, and Willey databases, 22 articles met the inclusion criteria for data extraction, with 18 studies eligible for meta-analysis.

The meta-analysis, employing the standardized mean difference as an effect size under a random effect model, examined various material properties, including flexural strength, impact strength, compressive strength, and hardness measurements. Subgroup analysis based on nanofiller concentration revealed improved outcomes at lower concentrations. Despite these promising findings, the review highlighted substantial heterogeneity and methodological variations among the studies, underscoring the need for standardized protocols in future research endeavors. While the optimized properties of low-concentration graphene in prosthodontic nanocomposites are notable, the current landscape lacks the consistency required for definitive clinical recommendations, emphasizing the necessity for further investigation and validation in clinical settings.

Moving forward, researchers are encouraged to prioritize the development and implementation of standardized protocols for evaluating graphene-enhanced prosthodontic materials. By focusing on methodological consistency and clinical validation, future studies can address the existing heterogeneity and establish a more robust foundation for evidence-based practice in prosthodontics. The systematic review emphasized the importance of rigorous research methodologies to advance understanding and application of graphene nanofillers in dental biomaterials, ultimately aiming to enhance the quality and efficacy of prosthodontic treatments.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/40988023/

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