Perio
Reports Vol. 21 No. 10 |
Perio Reports provides easy-to-read research summaries on topics of specific interest to clinicians.
Perio Reports research summaries will be included in each issue to keep you on the cutting edge
of dental hygiene science.
|
Poor oral health linked to COPD
Chronic obstructive pulmonary disease (COPD) is a
progressive disease making breathing difficult. It’s the
fourth leading cause of death in the United States.
According to the National Institutes of Health, more than
12 million people are currently diagnosed with COPD and
there are likely just as many more who are undiagnosed.
Smoking is a significant risk factor for COPD.
Researchers at the Capital Medical University in
Beijing, China evaluated patients at eight hospital in China
to determine if oral health and preventive behaviors were
linked to COPD. They examined 306 COPD patients and
328 controls who did not have the disease. COPD diagnosis
was confirmed by lung function examination. The average
age of subjects in both groups was 64 years old.
Significantly more former smokers were in the COPD
group. There were 47 current smokers in the COPD group
and 41 in the control group. Periodontal clinical indices
were measured and a questionnaire was completed by each
subject about oral health habits and beliefs.
Patients with COPD had fewer teeth and higher plaque
levels than controls. They also had greater loss of attachment
than controls, indicating more periodontal disease
history. Visiting the dentist within the last year was
reported by 42 percent of the COPD subjects compared to
59 percent of controls. Twenty-five percent of COPD subjects
reported having regular supragingival scaling compared
of 46 percent of controls.
Clinical Implications: Patients with COPD might
require more instruction in preventing periodontal
disease and actual periodontal therapy than patients
without COPD.
Wang, Z., Zhou, X., Zhang, J., Zhang, L., Song, Y., Hu, F., Wang, C.: Periodontal Health, Oral Health Behaviours, and Chronic Obstructive Pulmonary Disease. J Clin Perio 36: 750-755, 2009 |
|
CHX rinsing improves SRP outcomes
In the 1970s and 1980s research suggested that
supragingival plaque control every two weeks following SRP
would provide better clinical health outcomes and reduced
levels of sublingual microbes. Following these initial findings,
no additional research was done. More recently,
researchers have used molecular genetic testing to determine
that colonization of specific pathogens supragingivally
might in fact contribute to subgingival colonization. These
tests have identified the desirable microbial profile compatible
with periodontal health when weekly dental hygiene
visits are provided.
Researchers at Gaurulhos University in Brazil wanted to
know if twice daily rinsing with chlorhexidine (CHX) was as
beneficial as twice weekly supragingival plaque control visits
begun during SRP and carried out for 63 days. Sixty subjects
participated in the study, divided into three groups: SPR plus
twice daily CHX rinsing, SPR plus bi-weekly professional
plaque control plus a placebo rinse, and the control group of
SRP plus a placebo rinse. SRP was completed using local
anesthesia and primarily hand instruments. It was done by
periodontists in four to six, one-hour visits over at most, a 21-
day period.
Bi-weekly supragingival plaque control and CHX rinsing
both resulted in greater healing and reductions in subgingival
pathogens than SRP alone. At six months, those
rinsing with CHX showed slightly greater gain in clinical
attachment levels and more reduction in the number of
moderate to deep pockets. They also had more reductions in
pathogens, due in part to reductions in bacteria on the
tongue and mucous membranes.
Clinical Implications: Providing bi-weekly supragingival
plaque control during and after SRP and especially rinsing
twice daily with CHX provides for better healing.
Feres, M., Gursky, L., Faveri, M., Tsuzuki, C., Figueiredo, L.:
Clinical and Microbiological Benefits of strict Supragingival
Plaque Control as Part of the Active Phase of Periodontal
Therapy. J Clin Perio 36: 857-867, 2009. |
|
|
Photodynamic therapy best after repeated treatments
Photodynamic therapy (PDT) is now available in Canada
and Europe. PDT uses a photosensitizer solution injected
subgingivally that binds to bacteria. A cold laser light of a specific
wavelength is applied to the outside of the tissue. The
laser light activates the photosensitizer, changing the energy
levels of molecules and releases oxygen that destroys the bacteria.
This technology has been used in medicine to treat
tumors. It’s now used as an adjunct to SRP and has shown
reductions in bleeding on probing.
Researchers at the University of Bern in Switzerland
wanted to know if PDT would provide better healing when
used several times during maintenance therapy. The test
subjects were 10 maintenance patients with 70 residual
pockets measuring 5mm or more. The test group received
the PDT following debridement. The control group
received the same treatment, but with a non-activated laser.
Patients were seen for periodontal maintenance at three, six
and 12 months.
The greatest probing depth reductions were seen in the
test group with nearly a millimeter reduction compared to
none in the control group after six months. Bleeding scores
were reduced more in the test group, from 97 percent at
baseline to 64 percent at
three months, 67 percent at
six months and 77 percent
at 12 months. In the control
group, bleeding scores
remained constant at 84,
84, 90 and 87 percent.
The benefits of PDT
seem to be greatest at six
months following repeated
applications.
Clinical Implications: Photodynamic therapy,
when available in the United States might provide an
effective adjunct for periodontal maintenance patients.
Lulic, M., Görög, I., Salvi, G., Ramseier, C., Mattheos, N.,
Lang, N.: One-Year Outcomes of Repeated Adjunctive
Photodynamic Therapy during Periodontal Maintenance: A
Proof-of-Principle Randomized-Controlled Clinical Trial. J Clin
Perio. 36: 661-666, 2009. |
|
Maintenance therapy found cost effective
The goals of periodontal therapy are to stop disease progression,
achieve health in the supporting tissues and preserve the
teeth. Periodontal maintenance therapy is an essential part of
tooth preservation, however research studies rarely report the
number or costs of these visits.
Researchers at the University of Heidelberg in Germany
wanted to measure the financial costs of saving teeth through
periodontal maintenance therapy as compared to the alternatives
of tooth replacement. They evaluated nearly 100 patients
after 10 years of periodontal therapy.
The government established dental fee schedule was used
to determine costs for periodontal maintenance, SRP, and
various restorative procedures. Fees were totaled and divided
by the number of teeth to determine a per-tooth treatment
fee, which could then be compared to implant and restorative
fees.
Despite treatment plans calling for four maintenance visits a
year patients averaged 14 visits over 10 years with nine visits for
the non-compliers and 20 for the regular compliers. Some teeth
received no SRP during this time and others received SRP 14
times. Patients seen more frequently averaged a lower cost per
tooth compared to higher costs per tooth for those who had
more sporadic maintenance visits.
Tooth survival rate was 96.4 percent with 155 of 2,249 teeth
lost. Comparing maintenance fees with implant and prosthetic
fees showed significantly higher costs to replace lost teeth.
Several factors influenced costs per tooth, including tooth type,
initial bone loss, furcation involvement, abutment status, and
previous regenerative surgery.
Clinical
Implications: Periodontal maintenance therapy
provides high value for retaining teeth, compared to
implants and bridgework.
Pretzl, B., Wiedemann, D., Cosgarea, R., Kaltschmitt, J., Kim, T.,
Staehle, H., Eickholz, P.: Efforts and Costs of Tooth Preservation in
Supportive Periodontal Treatment in a German Population. J Clin
Perio 36: 669–676, 2009. |
|
Probiotic milk prevents gingivitis
Probiotics are live microorganisms that provide health
benefits. Most common are Lactobacillus acidophilus and
Bifidus that are often used to control
antibiotic induced diarrhea in children.
Probiotics are considered an alternative to
antibiotics in some cases. Researchers on
the Medical Faculty at the University of
Leipsig in Germany tested a probiotic milk
drink to determine if it would impact
experimental gingivitis.
Fifty medical and dental students participated
in the two-month study. Half
the group drank a probiotic milk drink
containing Lactobacillus casei daily and the
control group received no placebo drink.
The probiotic concentration was 100 billion
per 100 milliliter. Subjects were examined
at baseline, eight weeks and four days
later, after stopping all oral hygiene.
Clinical indices were recorded and in two
sites gingival crevicular fluid was collected.
After eight weeks, there were no differences
clinically between the test and
control groups for plaque levels or gingival
bleeding. Following four days without
oral hygiene, the test group had more
buccal and lingual plaque than the control
group and both groups had similar
bleeding scores.
Crevicular fluid analysis showed
changes in the test group that indicated
immunological changes. Both elastase and
myeloperoxidase activity were higher in
the control group before and after the four
days of experimental gingivitis, indicating
more inflammation.
Clinical Implications: The probiotics
added to the milk drink didn’t produce
measurable changes in the plaque
scores, but changes in subgingival
cytokines suggest a positive impact on
the immune response.
Staab, B., Eick, S., Knöfler, G., Jentsch, H.:
The Influence of a Probiotic Milk Drink on
the Development of Gingivitis: A Pilot Study. J Clin Perio 36:
850-856, 2009. |
|
Frequent DH visits important for those
with oralfacial clefts
The progression from embryo to
fetus occurs between the seventh
and 12th weeks of gestation. At this
time, the maxillary and palatal
processes merge to form the lips, the
palate and the alveolar process of
the maxilla. Cleft lip occurs with a
failure of the nasal and maxillary
processes to merge. Cleft palate is
caused by incomplete fusion of the palatal processes. Infants born with
oralfacial clefts require treatment by medical and dental specialists.
In 1959, a special program was developed at University Hospital in
Bern, Switzerland to provide multidisciplinary care for these infants. Twenty
years later, in 1979, 80 subjects were examined to determine periodontal
health adjacent to clefts.
While attachment levels were similar between cleft
and non-cleft sites, more bone loss was evident adjacent to clefts.
In 1993, 26 of the 80 subjects were examined again. None of them had
been receiving periodontal maintenance at the university, but instead were
seeing their general dentists once or twice a year. The cleft sites showed more
periodontal breakdown than the control sites. In 2004, 20 subjects were
available for reevaluation. Both cleft and control sites now had high plaque
and bleeding scores. More periodontal destruction was evident at cleft sites,
with a half of a millimeter more attachment loss compared to control sites.
Despite once or twice yearly visits to their general dentist, these people
did not effectively remove plaque and consequently suffered from periodontal
disease.
Clinical
Implications: Strict periodontal maintenance therapy schedules
should be followed for those with cleft palate and cleft lip, when
signs of periodontal disease are present to prevent disease progression.
Huynh-Ba, G., Brägger, Zwahlen, M, Lang, N., Salvi, G.: Periodontal Disease
Progression in Subjects with Orofacial Clefts Over a 25-Year Follow-Up Period.
J Clin Perio 36: 836-842, 2009. |
|