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Product Profile: Zimmer Dental

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Zimmer Dental

Questions every clinician should ask about grafting materials.

Many companies claim to provide safe tissue, but has their tissue process been validated by one or more independent laboratories?
Not all tissue processes have been validated for efficacy and consistency. The Tutoplast Process has been validated for inactivation of viruses and pathogens and for preservation of tissue biomechanics. Viral inactivation was validated by several independent laboratories.1

How much is known about the safety, reliability and consistency of the process used to treat these tissue grafts?
More than three million Tutoplast-processed tissue grafts have been implanted in patients for more than 40 years.

I am concerned about antibiotic reactions in patients. What residual antibiotics might I find in this graft material?
Three to five percent of the U.S. population has antibioticrelated allergies.2 Many grafts are delivered with a variety of residual antibiotics that must be checked against patient records prior to implantation. No Zimmer Dental grafts contain residual antibiotics.

Is this supplier able to meet all of my regenerative needs?
Zimmer Dental is a leader in regenerative offerings with one of the most comprehensive and high quality portfolios of solutions for dental grafting needs.

Does this company have a well-informed regenerative sales force?
Zimmer Dental has a nationwide team of regenerative sales specialists to help select indication-based regenerative materials for optimal patient outcomes.

Would I want to implant tissue in my patients that has not been terminally sterilized? Is this tissue terminally sterilized?
The Center for Disease Control recommended in 2004 that tissue banks process all tissue using sterilization (e.g. gamma irradiation) in order to eradicate bacteria spores (e.g. clostridium). 3 While some companies continue to produce aseptic rather than sterile grafts, all Zimmer Dental grafts are terminally sterilized. Note that "sterile packaged" does not mean a sterile product.

Will I truly get the same material every time I order? Is the material always processed using the same method by the same manufacturer?
To maximize consistency of results, all of Zimmer Dental's allograft materials are processed through the same tissue bank (RTI Biologics, Inc.) using the same controlled and validated process every single time.

For more information about Zimmer Dental, visit www.zimmerdental.com or call 800-854-7019.

References
  1. Schoepf C. Allograft safety: efficacy of the Tutoplast process. Intl Magazine of Oral Implantology. 2006;1:10-15
  2. Gruchalla RS, Pirmohamed M. Clinical practice. Antibiotic allergy. N Engl J Med. 2006;354:601-609
  3. Kainer MA, Linden JV, Whaley DN et al. Clostridium infections associated with musculoskeletal-tissue allografts. N Engl J Med. 2004;350:2564-2571
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