
No more ice cream. Forget about ice in your drinks (and
you’ll probably feel better if you use a straw). Make the hot
drinks lukewarm and stay away from sweets. No more mouth
breathing in cold weather and, whatever you do, don’t touch
that area! Have you ever suffered from dentin hypersensitivity?
Does it feel like root sensitivity is controlling your life or the
lives of your patients?
Since so many people simply live with sensitivity, we don’t
really know how many people are affected by it, but estimates
put it at approximately 35 percent of the general population,
with figures ranging between four and 57 percent. It is estimated
that 60 to 98 percent of periodontal patients with exposed
dentin are the largest group of suffers, followed by those who
whiten their teeth. My guess is, someone on your team probably
has root sensitivity.
Pain is caused by the movement of fluid within the dentinal
tubules, otherwise known as the hydrodynamic theory. Dentinal
tubules contain a plasma like fluid that conducts impulses from
the outside surface back to the fibers of the pulp. Movement of
the fluid causes stretching or compressing of the nerve fibers,
triggering pain. The dentinal tubule can be open at both ends,
in the mouth and at the pulp. Researchers have determined that
sensitive teeth have approximately eight times the number of
tubules in a given area compared to non-sensitive teeth and the
diameter of these tubules is nearly twice that of tubules found in
non-sensitive teeth.
To put this in perspective for patients, use the straw analogy.
Grab a handful of different size straws, big ones for cold drinks
and small ones for cocktails or coffee. Dentinal tubules come in
a variety of diameters, just like straws. Now imagine 30,000
straws – that’s how many dentinal tubules can be found in one
square millimeter of dentin. Your handful of open straw ends
represent the open dentinal tubules on an exposed root surface.
Unlike your empty straws, each dentinal tubule is filled with a
plasma-like fluid which represents 22 percent of the tooth’s
fluid. Additionally, an odontoblast process and nerve fibers
extend into each dentinal tubule from the pulp. Whatever
touches the ends of those straws will impact the fluid inside,
transmitting the stimuli to the nerves via movement of this fluid
and sending signals to the other end – in the tooth, that’s the
pulp. Hot, cold, touch, dehydration and chemicals that cause
osmotic changes can impact the fluid inside the straw or tubule.
To prevent stimulation of the fluid in the straws, we simply
block the end of each straw. This can be done by a coating over
the end, like plastic wrap, or using something that actually
enters the straw and plugs the ends, like a cork. Another
approach is to use a substance that enters the straw and numbs
up the nerve.
Normally, cementum blocks the tubules, but it is soft and
thin at the cemento-enamel junction and can easily be removed,
leaving the tubules open. Without cemental protection,
increased fluid flow will fill the dentinal tubules 10 times each
day. When dry absorbent paper is placed on a sensitive root surface,
fluid is drawn outward and pain is felt. If a moist paper is
placed instead, no pain is felt. A question yet unanswered is
what effect does blocking dentinal tubules have on the normal
flow of fluid within dentinal tubules.
Natural occlusion of open tubules occurs through calculus
formation and the deposition of salivary crystals, which explains
why sensitivity increases after periodontal instrumentation. In
office and at home therapeutic agents either enter the tubules
and modify the neural response of the pulp or form crystals
within the open tubules that reduce the size of the opening or
close it completely. In both cases, pain is reduced.
Laboratory studies that measure the effectiveness of therapeutic
hypersensitivity agents are done by microscopically
measuring tubule-opening sizes on extracted teeth before and
after application of a desensitizing agent. Theoretically, this
information provides proof of product effectiveness. Another
laboratory approach uses a silicone rubber impression material
to reproduce the dentinal surface for evaluation by scanning
electron microscopy. This approach was perfected on extracted
teeth in the laboratory and then impressions were made in the
mouth on teeth with sensitive cervical root surfaces prior to
extraction. Subjective hypersensitivity testing by the patients
prior to tooth extractions correlated with the number and size
of tubule openings captured in the impressions and on the
actual root surfaces.
Replicating conditions in the mouth for laboratory studies is
difficult, so studies are done by imbedding root chips with open
dentinal tubules into dentures. After test periods of seven days
to a month, the chips are removed and evaluated under a scanning
electron microscope. This method is used to measure the
length of time dentin tubules remain occluded following various
hypersensitivity treatments. It can also measure the natural crystal
formation that occurs with saliva.
In real life, clinicians must rely on the patient’s response to a
pain stimulus, usually cold air or touching with an explorer.
Surprisingly, many with root sensitivity don’t mention it, as they
think nothing can be done to treat it. In many cases sensitivity
is discovered while examining or treating the teeth.
Over instrumentation of root surfaces is a common cause of
root sensitivity and measurements show a doubling of root sensitivity
following periodontal surgery. Applying desensitizing
agents at the time of surgery is an effective way to prevent post
surgical sensitivity.
The popularity of tooth whitening has increased the incidence
of sensitivity so providing a desensitizing treatment either before
or after whitening will reduce pain. Many new whitening products
now contain ingredients to control sensitivity at the same time.
Diagnosis of root sensitivity should rule out endodontic
infections, caries, cracks, chips or broken fillings. When determining
the etiology of individual hypersensitivity cases, oral
hygiene, parafunctional habits and diet should be evaluated.
Sensitive areas need to be kept free from bacterial biofilm with
daily oral hygiene. Parafunctional habits like clenching, grinding
and mouth breathing should be evaluated. Dietary habits that
decrease oral pH need to be addressed as high acid foods, beverages
including fruit juices, energy drinks and wine, pickled
foods and sour acid candies all have erosive effects that can lead
to loss of mineralization thus opening dentinal tubules and causing
sensitivity. Toothbrushing after ingestion of low pH foods
and beverages has been shown to remove softened enamel and
cementum. Eating disorders causing vomiting and some occupations,
like wine tasting, and excessive use of acidic medicaments
like vitamin C or aspirin can be causative factors for
dentin hypersensitivity.
Treatment for dentin hypersensitivity should include patient
counseling regarding oral hygiene, parafunctional habits and
low pH foods and beverages. Products and treatments are categorized
into three levels. The first and easiest is the use of a
toothpaste designed for sensitive teeth. An increasing number of
sensitivity toothpastes are now available over the counter to
consumers. The most popular ingredient in sensitivity toothpastes
is potassium nitrate, which was first studied as a treatment
for dentinal hypersensitivity in the late 1960s by Dr. Milton
Hodosh. Potassium nitrate works not by blocking dentinal
tubules, but by action similar to a local anesthetic. Increased
concentration of extracellular potassium ions result in depolarization
of the nerve fiber membranes, thus
interfering with signal transmission to the
pulp. Elimination of dentin hypersensitivity
with toothpaste will take daily use for two to
three weeks plus continued use over time to
prevent recurrence.
NovaMin is a new ingredient used in both
toothpastes and professional treatment products.
NovaMin was invented by researchers at
the University of Maryland Dental School, as
an outgrowth of bone regeneration work.
Each microscopic NovaMin (calcium sodium
phosphosilicate) particle serves as a delivery
system for mineral ions that combine with
naturally occurring ions in saliva to form
hydroxyapatite crystals, that close dentinal
tubules and remineralize enamel.
If one of the sensitivity toothpastes doesn’t relieve the pain,
the next step is a clinician-dispensed product for use at home.
These products include high-level fluoride pastes and gels, usually
5,000ppm.
Professional treatments include paint-on and light cured
products, lasers, surgery and restorative options. The most popular
paint-on products have traditionally been fluorides, including
fluoride varnishes. Other paint-on products use metal salts
to occlude the tubules, including aluminum, potassium and
ferric oxaltes. Polishing pastes used by dental hygienists are now
available with ingredients to immediately block dentin tubules,
thus allowing further instrumentation. Colgate recently introduced
Sensitive Pro-Relief desensitizing polishing paste containing
Pro-Argin technology consisting of arginine and an
insoluble calcium carbonate that effectively forms crystals to
block the tubules with two three-second applications (this product
was previously available as ProClude).
Dentsply’s new polishing paste, NUPRO NUSolutions,
contains NovaMin, allowing for the blockage of tubules to
immediately relieve sensitivity. A normal prophylaxis using these
new polishing pastes for relief of dentin hypersensitivity transforms
a routine procedure into one that is now therapeutic.
Another paint-on option is the methacrylate polymers used
to seal cavity preparations or as composite bases. Next are the
oxalate and glutaraldehyde products. Light cured resins provide
another option that requires more clinician time but results in
sealing the open dentin tubules.
When localized dentin hypersensitivity doesn’t respond to
therapies already discussed, more invasive procedures are considered,
including Class V restorations, gingival grafts, iontophoresis
(delivering a low voltage charge force of sodium fluoride into
the dentin) and laser therapy.
When dentin hypersensitivity is diagnosed early, before significant
recession, minimally invasive therapy
options have the best chance of success.
Over the counter toothpastes and office dispensed
sensitivity products are the place to
start, together with in-office polishing
pastes and paint-on desensitizing solutions.
Long standing sensitivity with extensive
recession may require surgical intervention
to cover the exposed root surface with grafting
material to protect the open dentin
tubules. Many options are now available to
treat dentin hypersensitivity. Patients and
dental professionals who suffer with dentin
hypersensitivity have many new products
and approaches to eliminate the problem
once and for all. Bring on the cold drinks
and ice cream |