Young Permanent Molars: Brix 3000 vs. Papacárie Duo Study

Posted: September 23, 2025
A recent randomized clinical trial delved into the efficacy of chemo-mechanical caries removal (CMCR) agents in young permanent molars. The study compared Brix 3000 and Papacárie Duo to hand excavation in 108 children aged 8-10 years. Notably, the CMCR groups exhibited superior outcomes in reducing S. mutans and Lactobacilli counts post-treatment compared to hand excavation alone. The time taken for caries removal differed significantly, with hand excavation being quicker but associated with higher pain perception, highlighting the trade-offs between techniques.

Furthermore, the CMCR groups demonstrated enhanced restoration success rates at 6 and 12 months, surpassing the control group. Radiographic assessments also favored CMCR methods at the 12-month mark. Importantly, the study assessed oral health-related quality of life (OHRQoL) using CPQ8-10, revealing marked improvements across all groups post-treatment. Both Brix 3000 and Papacárie Duo showcased benefits in reducing cariogenic bacteria, alleviating pain, and promoting restoration longevity in immature permanent molars, underlining the potential of CMCR techniques in pediatric dental practice.

This comprehensive evaluation underscores the importance of adopting minimally invasive approaches like CMCR in managing deep carious lesions in young permanent molars. Dental professionals can leverage these findings to make informed decisions on treatment strategies, considering factors such as bacterial reduction, pain management, restoration success, and patient-reported outcomes. The study's registration on ClinicalTrials.gov further solidifies the validity and reliability of the results, offering valuable insights for enhancing clinical practices in pediatric dentistry.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/40988041/

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