Next-Gen Sequencing Boosts Odontogenic Abscess Pathogen ID, Clinical Impact

Posted: September 2, 2025
A study at University Hospital Bonn compared next-generation sequencing (NGS) to conventional methods for identifying microorganisms in odontogenic abscesses. NGS detected bacteria in 100% of swabs, compared to 68.1% with conventional methods. It identified a median of 8 bacterial genera per sample, primarily anaerobes, while conventional methods detected only 1. NGS also detected fungal organisms and antibiotic resistances more frequently. Prior antibiotic therapy was linked to reduced length of stay. NGS enhances detection of polymicrobial communities and antibiotic resistances, supporting tailored antimicrobial therapy.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/40892172/
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