Ergothioneine Boosts Neuronal Differentiation in Dental Stem Cells

Posted: September 3, 2025
A study explores the impact of ergothioneine on the neuronal differentiation of human dental pulp stem cells (hDPSCs). Ergothioneine, at a concentration of 500 µM, synergistically induced neuronal differentiation without cytotoxic effects. The differentiated cells exhibited neuronal characteristics and functional properties, suggesting potential for stem cell-based therapy in treating neurological diseases. This research highlights the promising role of ergothioneine in promoting neurogenic maturation through co-treatment with hDPSCs, offering a potential alternative for addressing various neurological conditions.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/40892799/
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