Exploring the Role of Circular RNAs in Inflammatory Pain of TMJOA

Posted: January 20, 2025
The study investigated the expression profile of circular RNAs in the thalamus of rats with temporomandibular osteoarthritis (TMJOA) to identify potential target markers for inflammation and chronic inflammatory pain in TMJOA. Through high-throughput sequencing and bioinformatics analysis, 425 differentially expressed circRNAs were identified, showing enrichment in pathways related to synapse development, protein signaling, and the MAPK signaling pathway. These findings suggest that circRNAs in the thalamus play a crucial role in the progression of TMJOA and could be valuable targets for gene therapy.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/39433265/
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