Exploring GCF Biomarkers in Periodontitis Progression and Treatment

Posted: January 4, 2025
This study investigated gingival crevicular fluid (GCF) biomarkers during periodontitis progression and after periodontal treatment. It identified inflammatory markers like IL-1β, MMP-8, IL-12p40, EGF, and VEGF associated with progression. Non-surgical periodontal therapy (NSPT) led to reductions in various biomarkers and distinct cytokine profiles based on baseline periodontal status were maintained post-treatment. The findings highlight the importance of GCF biomarkers in monitoring periodontal disease progression and treatment outcomes.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/39278722/
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