Innovative Use of Dental Pulp Stem Cell Spheroids for Periapical Lesion Repair

Posted: December 20, 2024
The article presents a groundbreaking approach to repopulate a simulated periapical lesion cavity using dental pulp stem cell spheroids with triggered osteoblastic differentiation. By culturing mesenchymal stem cells from human exfoliated deciduous teeth (SHED) in 3D spheroids, higher viability and uniform cellularity were achieved within the lesion cavity. This innovative technique showcases the potential of SHED-derived spheroids in regenerative endodontics for repairing periapical lesions.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/39699491/
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