Revolutionizing Tooth Organoid Generation with Cross-Linked Hydrogels

Posted: December 17, 2024
The article introduces the use of bioorthogonally cross-linked hydrogels as 3D matrixes for tooth organoid formation in vitro. By tuning the hydrogel properties, such as elasticity and stiffness, through varying gelatin concentration and stoichiometric ratio, successful growth kinetics and morphogenesis of tooth germs were achieved. This innovation provides a defined and tunable platform for tooth organoid engineering and modeling, offering significant potential for advancing dental research and practice.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/39532305/
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