Unlocking the Potential of Stem Cell Secretome in Restoring Dental Health for Diabetic Patients

Posted: December 1, 2024
The article explores the use of adipose tissue-derived mesenchymal stem cells (ADMSCs) secretome from healthy individuals to restore the adipo/osteogenic imbalance in dental pulp-derived MSCs from type 2 diabetes mellitus patients. They found that TNF-α influenced adipogenesis and osteogenesis in diabetic dental pulp-derived MSCs, but ADMSCs secretome enhanced osteogenesis and reduced adipogenesis. This innovative approach shows promise for future T2DM clinical management.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/39429485/
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