Unveiling a Rare RUNX2 Mutation in Cleidocranial Dysplasia Among Chinese Population

Posted: November 30, 2024
A novel splice site mutation in the RUNX2 gene was identified in a Chinese individual with cleidocranial dysplasia, leading to cranial and dental abnormalities. The study utilized Sanger sequencing and dPCR to confirm the mutation's impact on RUNX2 expression. This finding expands the understanding of RUNX2 mutations in cleidocranial dysplasia among the Chinese population, highlighting the importance of genetic considerations in dental anomalies.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/39584128/
Views: 4
Sponsors
Townie Perks
Townie® Poll
Who or what do you turn to for most financial advice regarding your practice?
  
The Dentaltown Team, Farran Media Support
Phone: +1-480-445-9710
Email: support@farranmedia.com
©2025 Dentaltown, a division of Farran Media • All Rights Reserved
9633 S. 48th Street Suite 200 • Phoenix, AZ 85044 • Phone:+1-480-598-0001 • Fax:+1-480-598-3450