Exploring Unique Toxic Pathways of Articaine on Schwann Cells

Posted: November 21, 2024
The study compared the effects of articaine and lidocaine on Schwann cells, revealing distinct toxic pathways and metabolic alterations induced by articaine. Articaine exhibited a more significant impact on Schwann cell oxygen consumption and triggered elevated levels of specific amino acids not observed with lidocaine. These metabolic and cellular responses provide insights into the differential toxicity and higher incidence of paresthesia associated with articaine, emphasizing the importance of understanding the unique properties of local anesthetics in dental practice.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/39580065/
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