Innovative Study Reveals the Impact of Stem Cells and Mandibular Advancement on Mandibular Growth and Condylar Cartilage Development in Adult Rats

Posted: November 19, 2024
This groundbreaking study explored the synergistic effects of odontogenic stem cells and mandibular advancement in promoting mandibular length and condylar cartilage development in adult rats. By injecting stem cells from the apical papilla (SCAPs) at varying frequencies during mandibular advancement, researchers observed significant growth and adaptive remodeling of the mandible and condylar cartilage. Rats with prolonged mandibular advancement or increased injection frequencies showed enhanced mandibular dimensions and thickened condylar cartilage layers. The study highlights the potential for continued growth and development of condylar cartilage in adult rats, emphasizing the efficacy of combining SCAP injections with mandibular advancement to stimulate mandibular condyle growth.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/39563452/
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