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Claire J
Claire J

Q: What is the active ingredient of doxycycline?

Q: What is the active ingredient of doxycycline?

3/22/2017 8:00:00 AM   |   Comments: 0   |   Views: 189

(A). Arestin
(B). Periochip
(C). Atridox


All the agents mentioned above are the most commonly-used locally-applied antimicrobial agents. They are used only after periodontal therapies have shown unsuccessful results (studies suggest that adjunct therapy alone does not improve periodontal health).

Adjunct therapies are very important to know for the National Dental Hygiene exams (NDBHE, NDHCE). The NBDHE guidelines specifically say that you will see questions related to the topic of “adjunct therapy.” Here are more details from StudentRDH National Boards as a mini-review in the chapter on Periodontology.

  • Periostatsystemic delivery of a 20 mg capsule of doxycycline hyclate (oral administration).
  • Arestinmicrospheres of minocycline (derivative of tetracycline) are inserted into the pocket (by cannula tip).
    • Microspheres dissolve - no need to remove anything from the pocket.
    • Bacteriostatic for up to 14 days.
    • Do not brush for 12 hours and do not floss at sites for 10 days.
  • Atridox: doxycycline gel (derivative of tetracycline) is inserted into the pocket (by cannula tip).
    • Gel dissolves - no need to remove anything from the pocket.
    • Do not brush or floss at sites for 7 days.
  • Periochip: chlorhexidine chip is inserted into the periodontal pocket.
    • Chip may not properly fit into the pocket, especially if the pocket is shallow (less than 5 mm).
    • Chip is dissolved, no need to remove anything from the pocket.
    • Do not floss at sites for 10 days.
  • Tetracycline HCL fibers: tetracycline soaked cord is packed inside the pocket and retained with adhesive.

Answer: (C). Atridox

Atridox and Arestin can be confusing because they sound pretty similar. Take the “AR” comes from ARestin and the “M” from Minocycline. Then you have “ARM,” like your right arm. For Atridox, see the “X” in AtridoX and the “X” in doXycycline. Hope this helps memorize at least those two agents for the dental hygiene board exams (NBDHE, NDHCE). Keep powering through every day to get ready for the BIG DAY! Always wish you the very best. You can forward this email to your friends and remind them to click here to sign up for StudentRDH Vitamins.


Mini Boards Reviews for the National + Local Anesthesia Dental Hygiene Boards. Weekly Sample Questions at www.StudentRDH.com. Find COMPLETE review courses too. “I wish I did not spend money on other review courses!” – Bethany, Bergen CC, March 2016

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